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MyGenomeBox allow to use your raw genetic data form Gene2me, 23andMe, AncestryDNA, FamilyTreeDNA and VCF to create personalized genetic reports that will help you find the genetic information that`s right for you.
Once you upload your files, you can purchase DNA Apps.
* You cannot purchase DNA apps if you have uploaded an unusable file. * If you still can not purchase DNA Apps after uploading your files, try re- login after logging out.
Inheritance of a pathogenic mutation in the BRCA1 or BRCA2 gene results in hereditary breast and ovarian cancer (HBOC) syndrome, an autosomal dominant disorder related primarily to increased risk of early-onset, breast and ovarian cancer in females. HBOC syndrome accounts for about 5-7% of all breast cancer cases. The average cumulative risks in BRCA1 mutation carriers by age 70 are 65% for breast cancer and 39% for ovarian cancer. The corresponding estimates for BRCA2 are 45% for breast cancer and 11% for ovarian cancer. BRCA1 and BRCA2 mutation carriers have been reported to have 4.5-fold and 3.4 fold increased risks of contralateral breast cancer compared to noncarriers, respectively. BRCARE test is designed to detect mutations in BRCA1 and BRCA2.
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